TOPBP1 抗体 (AA 1253-1522)
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Quick Overview for TOPBP1 抗体 (AA 1253-1522) (ABIN7150350)
抗原
See all TOPBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1253-1522
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原理
- TOPBP1 Antibody
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human DNA topoisomerase 2-binding protein 1 protein (1253-1522AA)
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亚型
- IgG
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anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1327-1435) antibody
TOPBP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D12 unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1-250) antibodyTOPBP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1-246) antibodyTOPBP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1327-1435) antibodyTOPBP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (Internal Region) antibodyTOPBP1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (Internal Region) antibodyTOPBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1-246) antibodyTOPBP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (pSer1159) antibodyTOPBP1 适用: 人 DB 宿主: 兔 Polyclonal RB36342 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))
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别名
- TOPBP1
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背景
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Background: Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR.
Aliases: DNA topoisomerase 2 binding protein 1 antibody, DNA topoisomerase 2-binding protein 1 antibody, DNA topoisomerase II binding protein 1 antibody, DNA topoisomerase II binding protein antibody, DNA topoisomerase II-beta-binding protein 1 antibody, DNA topoisomerase II-binding protein 1 antibody, DNA topoisomerase IIbeta binding protein 1 antibody, Hypothetical protein KIAA0259 [Fragment] antibody, KIAA0259 antibody, TOP2BP1 antibody, TOPB1_HUMAN antibody, TOPBP 1 antibody, TopBP1 antibody, Topoisomerase (DNA) II binding protein 1 antibody, Topoisomerase II binding protein 1 antibody
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UniProt
- Q92547
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途径
- Chromatin Binding
抗原
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