-
- 抗原 See all TOPBP1 抗体
- TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This TOPBP1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- TOPBP1 Antibody detects endogenous levels of total TOPBP1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TOPBP1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TOPBP1 Primary Antibody
-
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1253-1522) antibody
TOPBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) antibodyTOPBP1 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1327-1435) antibodyTOPBP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D12 unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1-100) antibodyTOPBP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1-250) antibodyTOPBP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1-246) antibodyTOPBP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1253-1522) antibodyTOPBP1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) antibodyTOPBP1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1327-1435) antibodyTOPBP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (Internal Region) antibodyTOPBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))
- 别名
- TOPBP1 (TOPBP1 产品)
- 别名
- RGD1562949 antibody, TOPBP1 antibody, cut5 antibody, F2P24.3 antibody, F2P24_3 antibody, meiosis defective 1 antibody, TOP2BP1 antibody, 1110031N14Rik antibody, 2810429C13Rik antibody, AI256758 antibody, D430026L04Rik antibody, mKIAA0259 antibody, TopBP1-A antibody, TopBP1-B antibody, Xmus101 antibody, XtopBP antibody, mus101 antibody, top2bp1 antibody, DNA topoisomerase II binding protein 1 antibody, topoisomerase (DNA) II binding protein 1 antibody, dna topoisomerase ii binding protein 1 (IC) antibody, transcription coactivator antibody, DNA topoisomerase II binding protein 1 L homeolog antibody, Topbp1 antibody, topbp1 antibody, TOPBP1 antibody, MEI1 antibody, topbp1.L antibody
- 背景
-
Description: Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR (PubMed:16530042).
Gene: TOPBP1
- 分子量
- 173kDa
- 基因ID
- 11073
- UniProt
- Q92547
- 途径
- Chromatin Binding
-
You are here:
