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DDIT3 抗体 (AA 1-169)

Name: DDIT3 抗体 (AA 1-169)
Brand: antibodies-online
SKU: ABIN7150132
Availability: OutOfStock

This anti-DDIT3 antibody is a 兔多克隆 antibody detecting DDIT3 in IHC, ELISA 和 IF. Suitable for 人.

Immunohistochemistry of paraffin-embedded human liver cancer using ABIN7150132 at dilution of 1:100 (DDIT3 抗体 (AA 1-169))

IHC

Immunohistochemistry of paraffin-embedded human gastric cancer using ABIN7150132 at dilution of 1:100 (DDIT3 抗体 (AA 1-169))

IHC

Immunohistochemistry of paraffin-embedded human colon cancer using ABIN7150132 at dilution of 1:100 (DDIT3 抗体 (AA 1-169))

IHC

Immunofluorescent analysis of PC-3 cells using ABIN7150132 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) (DDIT3 抗体 (AA 1-169))

4 images

产品编号 ABIN7150132

发货至: 中国

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中国
北京 101111

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Beijing Economic Technological Development Area

Room 801-803

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Quick Overview for DDIT3 抗体 (AA 1-169) (ABIN7150132)

抗原

See all DDIT3 抗体

DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

人

宿主

兔

克隆类型

多克隆

标记

This DDIT3 antibody is un-conjugated

应用范围

Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Discover our top product DDIT3 Primary Antibody

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AA 1-169

原理

DDIT3 Antibody

纯化方法

Protein G purified

纯度

>95 %

免疫原

Recombinant Human DNA damage-inducible transcript 3 protein (1-169AA)

亚型

IgG
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (C-Term) antibody
DDIT3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-169) antibody
DDIT3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (N-Term) antibody
DDIT3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (pSer30) antibody
DDIT3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (N-Term) antibody
DDIT3 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 120-149), (C-Term) antibody
DDIT3 适用: 人, 小鼠 WB, IF, FACS 宿主: 兔 Polyclonal RB13788 unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (Ser301) antibody
DDIT3 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) antibody
KD Validated DDIT3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2955 unconjugated Recombinant Antibody

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-90) antibody
DDIT3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G3 unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 75-168) antibody
DDIT3 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Liquid

缓冲液

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

别名

DDIT3

背景

Background: Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates, expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response.
Aliases: C/EBP homologous protein antibody, C/EBP Homology Protein antibody, C/EBP zeta antibody, C/EBP-homologous protein 10 antibody, C/EBP-homologous protein antibody, CCAAT/enhancer binding protein homologous protein antibody, CEBPZ antibody, CHOP 10 antibody, CHOP antibody, CHOP-10 antibody, CHOP10 antibody, DDIT 3 antibody, DDIT-3 antibody, Ddit3 antibody, DDIT3_HUMAN antibody, DNA Damage Inducible Transcript 3 antibody, DNA damage-inducible transcript 3 protein antibody, GADD 153 antibody, GADD153 antibody, Growth Arrest and DNA Damage Inducible Protein 153 antibody, Growth arrest and DNA damage inducible protein GADD153 antibody, Growth arrest and DNA damage-inducible protein GADD153 antibody, MGC4154 antibody

UniProt

P35638

途径

Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis