DKK4 抗体 (AA 19-224)
Quick Overview for DKK4 抗体 (AA 19-224) (ABIN7149890)
抗原
See all DKK4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 19-224
-
交叉反应
- 人
-
纯化方法
- Antigen Affinity Purified
-
免疫原
- Recombinant Human Dickkopf-related protein 4 protein (19-224AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: IHC:1:20-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- DKK4 (Dickkopf Homolog 4 (Xenopus Laevis) (DKK4))
-
别名
- DKK4
-
背景
-
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Aliases: Dickkopf 4 antibody, Dickkopf gene 4 antibody, Dickkopf homolog 4 (Xenopus laevis) antibody, Dickkopf homolog 4 antibody, Dickkopf related protein 4 antibody, Dickkopf-4 antibody, Dickkopf-related protein 4 short form antibody, Dickkopf4 antibody, DKK 4 antibody, Dkk-4 antibody, DKK4 antibody, DKK4_HUMAN antibody, hDkk 4 antibody, hDkk-4 antibody, hDkk4 antibody, MGC129562 antibody, MGC129563 antibody
-
UniProt
- Q9UBT3
-
途径
- WNT signaling
抗原
-