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CST3 抗体

This anti-CST3 antibody is a 小鼠 单克隆 antibody detecting CST3 in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7148973
发货至: 中国

Quick Overview for CST3 抗体 (ABIN7148973)

抗原

See all CST3 抗体
CST3 (Cystatin C (CST3))

适用

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宿主

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小鼠

克隆类型

  • 95
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单克隆

标记

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This CST3 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)

克隆位点

3A1B7
  • 交叉反应

    纯化方法

    Protein G purified

    免疫原

    Recombinant Human Cystatin C protein

    亚型

    IgG2b
  • 应用备注

    Recommended dilution:IHC:1:50-1:500,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CST3 (Cystatin C (CST3))

    别名

    CST3

    背景

    Background: Defects in CST3 are the cause of amyloidosis type 6 (AMYL6) [MIM:105150], also known as hereditary cerebral hemorrhage with amyloidosis (HCHWA), cerebral amyloid angiopathy (CAA) or cerebroarterial amyloidosis Icelandic type. AMYL6 is a hereditary generalized amyloidosis due to cystatin C amyloid deposition. Cystatin C amyloid accumulates in the walls of arteries, arterioles, and sometimes capillaries and veins of the brain, and in various organs including lymphoid tissue, spleen, salivary glands, and seminal vesicles. Amyloid deposition in the cerebral vessels results in cerebral amyloid angiopathy, cerebral hemorrhage and premature stroke. Cystatin C levels in the cerebrospinal fluid are abnormally low.Genetic variations in CST3 are associated with age-related macular degeneration type 11 (ARMD11) [MIM:611953]. ARMD is a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane.

    Aliases: CysC,Cystatin-3,Gamma-trace,Neuroendocrine basic polypeptide,Post-gamma-globulin

    UniProt

    P01034
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