CDK3 抗体 (AA 220-297)
Quick Overview for CDK3 抗体 (AA 220-297) (ABIN7148881)
抗原
See all CDK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-297
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Cyclin-dependent kinase 3 protein (220-297AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CDK3 (Cyclin-Dependent Kinase 3 (CDK3))
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别名
- CDK3
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背景
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Background: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle, involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.
Aliases: Cdk 3 antibody, Cdk3 antibody, CDK3_HUMAN antibody, CDKN3 antibody, Cell division kinase 3 antibody, Cell division protein kinase 3 antibody, Cyclin dependent kinase 3 antibody, Cyclin-dependent kinase 3 antibody, OTTHUMP00000206828 antibody, p36 antibody
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UniProt
- Q00526
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途径
- Cell Division Cycle
抗原
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