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CDK3 抗体 (C-Term)

CDK3 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260712
发货至: 中国
  • 抗原 See all CDK3 抗体
    CDK3 (Cyclin-Dependent Kinase 3 (CDK3))
    抗原表位
    • 15
    • 8
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 52
    • 7
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 51
    • 1
    克隆类型
    • 51
    • 1
    多克隆
    标记
    • 20
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDK3 antibody is un-conjugated
    应用范围
    • 41
    • 22
    • 13
    • 13
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    CDK3 Antibody detects endogenous levels of total CDK3.
    预测反应
    Pig,Bovine,Sheep,Rabbit
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CDK3, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CDK3 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • Wang, Xi, Sun, Zhang, Jiang, He, Li: "CDK3 is a major target of miR-150 in cell proliferation and anti-cancer effect." in: Experimental and molecular pathology, Vol. 102, Issue 2, pp. 181-190, (2017) (PubMed).

  • 抗原
    CDK3 (Cyclin-Dependent Kinase 3 (CDK3))
    别名
    CDK3 (CDK3 产品)
    别名
    2310050O10Rik antibody, Cdk3 antibody, cyclin dependent kinase 3 antibody, cyclin-dependent kinase 3 antibody, cyclin-dependent kinase 3, pseudogene antibody, CDK3 antibody, cgd3_1510 antibody, Chro.30182 antibody, Cdk3-ps antibody
    背景

    Description: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle, involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.

    Gene: CDK3

    分子量
    35 kDa
    基因ID
    1018
    UniProt
    Q00526
    途径
    Cell Division Cycle
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