CDK12 抗体 (AA 1309-1490) (Biotin)
Quick Overview for CDK12 抗体 (AA 1309-1490) (Biotin) (ABIN7148852)
抗原
See all CDK12 (CRKRS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1309-1490
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Cyclin-dependent kinase 12 protein (1309-1490AA)
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亚型
- IgG
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anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (AA 80-290) antibody
CRKRS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (AA 1281-1380) antibodyCRKRS 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (AA 1281-1380) antibodyCRKRS 适用: 人 ELISA, WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 3C1 unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) antibodyCRKRS 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (Internal Region) antibodyCRKRS 适用: 人, 犬, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (AA 1281-1380) antibodyCRKRS 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (AA 1309-1490) antibodyCRKRS 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (C-Term) antibodyCRKRS 适用: 人, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))
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别名
- CDK12
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背景
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Background: Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates \'Ser-5\' in CTD repeats that are already phosphorylated at \'Ser-7\', but can also phosphorylate \'Ser-2\'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
Aliases: arginine/serine-rich antibody, Cdc2 related kinase arginine/serine rich antibody, CDC2 related protein kinase 7 antibody, Cdc2-related kinase antibody, CDC2-related protein kinase 7 antibody, Cdk12 antibody, CDK12_HUMAN antibody, Cell division cycle 2 related protein kinase 7 antibody, Cell division cycle 2-related protein kinase 7 antibody, Cell division protein kinase 12 antibody, CRK7 antibody, CRKR antibody, CrkRS antibody, Cyclin-dependent kinase 12 antibody, EC 2.7.11.22 antibody, hCDK12 antibody, kiaa0904 antibody, Pksc antibody
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UniProt
- Q9NYV4
抗原
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