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- 抗原 See all CDK12 (CRKRS) 抗体
- CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))
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抗原表位
- C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK12 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 特异性
- CD2L7 Antibody detects endogenous levels of total CD2L7.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CD2L7, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CRKRS Primary Antibody
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anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (AA 80-290) antibody
CRKRS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (AA 1281-1380) antibodyCRKRS 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (AA 1281-1380) antibodyCRKRS 适用: 人 ELISA, WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 3C1 unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) antibodyCRKRS 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (Internal Region) antibodyCRKRS 适用: 人, 犬, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (AA 1281-1380) antibodyCRKRS 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) (AA 1309-1490) antibodyCRKRS 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))
- 别名
- CDK12 (CRKRS 产品)
- 别名
- AC017581 antibody, CG7597 antibody, Dmel\\CG7597 antibody, anon-WO0140519.165 antibody, cg7597 antibody, dCDK12 antibody, gi24668141 antibody, CRK7 antibody, CRKR antibody, CRKRS antibody, hCDK12 antibody, 1810022J16Rik antibody, AI646528 antibody, Crk7 antibody, Crkrs antibody, D11Ertd752e antibody, Pksc antibody, Cyclin-dependent kinase 12 antibody, cyclin dependent kinase 12 antibody, cyclin-dependent kinase 12 antibody, Cdk12 antibody, CDK12 antibody
- 背景
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Description: Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
Gene: CDK12
- 分子量
- 164 kDa
- 基因ID
- 51755
- UniProt
- Q9NYV4
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