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ATF6 抗体 (AA 1-194) (Biotin)

This anti-ATF6 antibody is a 兔 多克隆 antibody detecting ATF6 in ELISA. Suitable for 人.
产品编号 ABIN7148806
发货至: 中国
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Quick Overview for ATF6 抗体 (AA 1-194) (Biotin) (ABIN7148806)

抗原

See all ATF6 抗体
ATF6 (Activating Transcription Factor 6 (ATF6))

适用

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宿主

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克隆类型

  • 86
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多克隆

标记

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This ATF6 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

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    AA 1-194

    原理

    ATF6 Antibody, Biotin conjugated

    纯化方法

    Antigen Affinity purified & Affinity purified

    纯度

    >95 %

    免疫原

    Recombinant Human Cyclic AMP-dependent transcription factor ATF-6 alpha protein (1-194AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ATF6 (Activating Transcription Factor 6 (ATF6))

    别名

    ATF6

    背景

    Background: Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5\'-CCAC[GA]-3\'half of the ER stress response element (ERSE) (5\'-CCAAT-N(9)-CCAC[GA]-3\') and of ERSE II (5\'-ATTGG-N-CCACG-3\'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.

    Aliases: Activating transcription factor 6 alpha antibody, Activating transcription factor 6 antibody, ATF 6 antibody, ATF6 alpha antibody, ATF6 antibody, ATF6-alpha antibody, ATF6A antibody, ATF6A_HUMAN antibody, cAMP dependent transcription factor ATF 6 alpha antibody, cAMP-dependent transcription factor ATF-6 alpha antibody, Cyclic AMP dependent transcription factor ATF 6 alpha antibody, DKFZp686P2194 antibody, ESTM49 antibody, FLJ21663 antibody, Processed cyclic AMP dependent transcription factor ATF 6 alpha antibody, Processed cyclic AMP-dependent transcription factor ATF-6 alpha antibody

    UniProt

    P18850

    途径

    ER-Nucleus Signaling, Unfolded Protein Response
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