H2AFY 抗体 (AA 123-372)
Quick Overview for H2AFY 抗体 (AA 123-372) (ABIN7148560)
抗原
See all H2AFY 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 123-372
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Core histone macro-H2A.1 protein (123-372AA)
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亚型
- IgG
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anti-H2A Histone Family, Member Y (H2AFY) (AA 109-369) antibody
H2AFY 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (AA 123-372) antibodyH2AFY 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) antibodyH2AFY 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (AA 144-193) antibodyH2AFY 适用: 人, 大鼠, 小鼠, Cow, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (N-Term) antibodyH2AFY 适用: 人, 大鼠, 小鼠, Cow, 马, 犬, 豚鼠, 兔, Pig, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (AA 36-85) antibodyH2AFY 适用: 人, 大鼠, 小鼠, Cow, 马, 犬, 豚鼠, 兔, Pig, 猴, 斑马鱼, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (Middle Region) antibodyH2AFY 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (N-Term) antibodyH2AFY 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- H2AFY (H2A Histone Family, Member Y (H2AFY))
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别名
- H2AFY
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背景
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Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Involved in stable X chromosome inactivation. Inhibits the binding of transcription factors and interferes with the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces a hypoacetylated state of chromatin. In addition, isoform 1, but not isoform 2, binds ADP-ribose and O-acetyl-ADP-ribose, and may be involved in ADP-ribose-mediated chromatin modulation.
Aliases: Core histone macro h2a.1 antibody, Core histone macro-H2A.1 antibody, H2A histone family member Y antibody, H2A.y antibody, H2A/y antibody, H2AF12M antibody, H2AFJ antibody, H2afy antibody, H2AY_HUMAN antibody, Histone H2A.Y antibody, Histone macroH2A1 antibody, Histone macroH2A1.1 antibody, Histone macroH2A1.2 antibody, Macroh2a1 antibody, MACROH2A1.1 antibody, MacroH2A1.2 antibody, Medulloblastoma antigen MU MB 50.205 antibody, Medulloblastoma antigen MU-MB-50.205 antibody, mH2a antibody, mH2A1 antibody
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UniProt
- O75367
抗原
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