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GPS1 抗体 (AA 222-491)

This anti-GPS1 antibody is a 兔 多克隆 antibody detecting GPS1 in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7148491
发货至: 中国

Quick Overview for GPS1 抗体 (AA 222-491) (ABIN7148491)

抗原

See all GPS1 抗体
GPS1 (G Protein Pathway Suppressor 1 (GPS1))

适用

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宿主

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克隆类型

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多克隆

标记

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This GPS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    AA 222-491

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human COP9 signalosome complex subunit 1 protein (222-491AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    GPS1 (G Protein Pathway Suppressor 1 (GPS1))

    别名

    GPS1

    背景

    Background: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction.

    Aliases: COP9 signalosome complex subunit 1 antibody, COP9 signalosome subunit 1 antibody, COPS1 antibody, CSN 1 antibody, CSN1_HUMAN antibody, FUS6/COP11, Arabidopsis, homolog of antibody, G protein pathway suppressor 1 antibody, GPS-1 antibody, Gps1 antibody, JAB1-containing signalosome subunit 1 antibody, Protein GPS1 antibody, Protein MFH antibody, SGN1 antibody, Signalosome subunit 1 antibody

    UniProt

    Q13098

    途径

    Cell Division Cycle
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