C4B 抗体 (AA 1454-1744)
Quick Overview for C4B 抗体 (AA 1454-1744) (ABIN7148365)
抗原
See all C4B (C4b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1454-1744
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Complement C4-B protein (1454-1744AA)
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亚型
- IgG
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anti-Complement Component C4b (C4b) (AA 126-366) antibody
C4b 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4b (C4b) (AA 680-756) antibodyC4b 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4b (C4b) (AA 1347-1446) antibodyC4b 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-Complement Component C4b (C4b) (AA 19-333) antibodyC4b 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4b (C4b) antibodyC4b 适用: 人 IHC, IF, StM 宿主: 小鼠 Monoclonal SPM545 unconjugated
anti-Complement Component C4b (C4b) (AA 144-193) antibodyC4b 适用: 人, 小鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4b (C4b) (AA 655-684) antibodyC4b 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- C4B (C4b) (Complement Component C4b (C4b))
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别名
- C4B
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背景
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Background: Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Ref.16 Ref.17 Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Aliases: Basic complement C4 antibody, C2B5 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 antibody, C4b antibody, C4B1 antibody, C4B2 antibody, C4B3 antibody, CO4B_HUMAN antibody, Complement C4 gamma chain antibody, Complement component 4B antibody, CPAMD3 antibody
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UniProt
- P0C0L5
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途径
- Complement System
抗原
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