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BHLHE41 抗体 (AA 185-285) (HRP)

This anti-BHLHE41 antibody is a 兔 多克隆 antibody detecting BHLHE41 in ELISA. Suitable for 人.
产品编号 ABIN7147844
发货至: 中国
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Quick Overview for BHLHE41 抗体 (AA 185-285) (HRP) (ABIN7147844)

抗原

See all BHLHE41 抗体
BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))

适用

  • 42
  • 22
  • 15
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 33
  • 8
  • 1

克隆类型

  • 35
  • 7
多克隆

标记

  • 27
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BHLHE41 antibody is conjugated to HRP

应用范围

  • 31
  • 20
  • 7
  • 6
  • 4
  • 4
  • 1
  • 1
ELISA
  • 抗原表位

    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 185-285

    原理

    BHLHE41 Antibody, HRP conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Class E basic helix-loop-helix protein 41 protein (185-285AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))

    别名

    BHLHE41

    背景

    Background: Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer by competing for the binding to E-box elements (5\'-CACGTG-3\') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity.

    Aliases: Basic helix-loop-helix domain containing class B3 antibody, BHE41_HUMAN antibody, bHLH protein DEC2 antibody, bHLHB3 antibody, bHLHe41 antibody, Class B basic helix loop helix protein 3 antibody, Class B basic helix-loop-helix protein 3 antibody, Class E basic helix-loop-helix protein 41 antibody, DEC2 antibody, Differentially expressed in chondrocytes protein 2 antibody, Enhancer of split and hairy related protein 1 antibody, Enhancer-of-split and hairy-related protein 1 antibody, hDEC2 antibody, Moderately similar to basic-helix loop helix protein M.musculus antibody, SHARP-1 antibody

    UniProt

    Q9C0J9

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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