BHLHE41 抗体 (N-Term)
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- 抗原 See all BHLHE41 抗体
- BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BHLHE41 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- BHLHB3 Antibody detects endogenous levels of total BHLHB3.
- 预测反应
- Pig,Bovine,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human BHLHB3, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product BHLHE41 Primary Antibody
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anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 203-282) antibody
BHLHE41 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 185-285) antibodyBHLHE41 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 203-282) antibodyBHLHE41 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (N-Term) antibodyBHLHE41 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 216-265) antibodyBHLHE41 适用: 人, 犬, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 1-50) antibodyBHLHE41 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 120-280) antibodyBHLHE41 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (N-Term) antibodyBHLHE41 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
- 别名
- BHLHE41 (BHLHE41 产品)
- 别名
- BHLHB3 antibody, dec2 antibody, bhlhb3 antibody, sharp1 antibody, sharp-1 antibody, MGC108143 antibody, DEC2 antibody, SHARP1 antibody, hDEC2 antibody, 6430520M22Rik antibody, Bhlhb2l antibody, Bhlhb3 antibody, Sharp1 antibody, Dec2 antibody, SHARP-1 antibody, basic helix-loop-helix family member e41 antibody, basic helix-loop-helix family, member e41 antibody, BHLHE41 antibody, bhlhe41 antibody, Bhlhe41 antibody
- 背景
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Description: Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer by competing for the binding to E-box elements (5'-CACGTG-3') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity.
Gene: BHLHE41
- 分子量
- 50 kDa
- 基因ID
- 79365
- UniProt
- Q9C0J9
- 途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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