IRG1 抗体 (AA 57-257) (HRP)
Quick Overview for IRG1 抗体 (AA 57-257) (HRP) (ABIN7147804)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 57-257
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Cis-aconitate decarboxylase protein (57-257AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IRG1 (Immunoresponsive Gene 1 (IRG1))
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别名
- ACOD1
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背景
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Background: Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
Aliases: ACOD1 antibody, Aconitate decarboxylase 1 antibody, Aconitate decarboxylase antibody, CAD antibody, Cis aconitate decarboxylase antibody, Immune responsive gene 1 protein homolog antibody, Immune-responsive gene 1 protein homolog antibody, Immunoresponsive 1 homolog (mouse) antibody, Irg1 antibody, IRG1_HUMAN antibody, OC116 antibody, OPTB1 antibody, TCTIRC7 antibody
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UniProt
- A6NK06
抗原
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