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- 抗原 See all IRG1 products
- IRG1 (Immunoresponsive Gene 1 (IRG1))
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抗原表位
- AA 57-257
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IRG1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Cis-aconitate decarboxylase protein (57-257AA)
- 亚型
- IgG
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anti-Immunoresponsive Gene 1 (IRG1) antibody
IRG1 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Immunoresponsive Gene 1 (IRG1) (C-Term) antibodyIRG1 适用: 人 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- IRG1 (Immunoresponsive Gene 1 (IRG1))
- 别名
- ACOD1 (IRG1 产品)
- 别名
- CAD antibody, AI323667 antibody, aconitate decarboxylase 1 antibody, ACOD1 antibody, Acod1 antibody
- 背景
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Background: Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
Aliases: ACOD1 antibody, Aconitate decarboxylase 1 antibody, Aconitate decarboxylase antibody, CAD antibody, Cis aconitate decarboxylase antibody, Immune responsive gene 1 protein homolog antibody, Immune-responsive gene 1 protein homolog antibody, Immunoresponsive 1 homolog (mouse) antibody, Irg1 antibody, IRG1_HUMAN antibody, OC116 antibody, OPTB1 antibody, TCTIRC7 antibody
- UniProt
- A6NK06
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