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INO80 抗体 (AA 1365-1495) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-INO80 antibody specifically detects INO80 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7147694
发货至: 中国
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Quick Overview for INO80 抗体 (AA 1365-1495) (Biotin) (ABIN7147694)

抗原

See all INO80 抗体
INO80 (INO80 Homolog (INO80))

适用

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宿主

  • 17
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克隆类型

  • 18
多克隆

标记

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This INO80 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

    • 4
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    AA 1365-1495

    原理

    INO80 Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Chromatin-remodeling ATPase INO80 protein (1365-1495AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    INO80 (INO80 Homolog (INO80))

    别名

    INO80

    背景

    Background: ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20855601, PubMed:20237820). Binds DNA (PubMed:16298340, PubMed:21303910). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed:16230350, PubMed:21303910). Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed:17721549). Involved in UV-damage excision DNA repair (PubMed:20855601). The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation (PubMed:20687897). Involved in DNA replication (PubMed:20237820). Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle (PubMed:20237820).

    Aliases: DNA helicase INO80 antibody, hINO80 antibody, homolog of yeast INO80 antibody, INO80 antibody, INO80 complex subunit A antibody, INO80 homolog antibody, INO80_HUMAN antibody, INO80A antibody, INOC1 antibody, KIAA1259 antibody, Putative DNA helicase INO80 complex homolog 1 antibody

    UniProt

    Q9ULG1

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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