INO80 抗体 (AA 1365-1495)
Quick Overview for INO80 抗体 (AA 1365-1495) (ABIN7147693)
抗原
See all INO80 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1365-1495
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原理
- INO80 Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Chromatin-remodeling ATPase INO80 protein (1365-1495AA)
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亚型
- IgG
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anti-INO80 Homolog (INO80) antibody
INO80 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-INO80 Homolog (INO80) (AA 1400-1450) antibodyINO80 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔 IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- INO80 (INO80 Homolog (INO80))
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别名
- INO80
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背景
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Background: ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20855601, PubMed:20237820). Binds DNA (PubMed:16298340, PubMed:21303910). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed:16230350, PubMed:21303910). Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed:17721549). Involved in UV-damage excision DNA repair (PubMed:20855601). The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation (PubMed:20687897). Involved in DNA replication (PubMed:20237820). Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle (PubMed:20237820).
Aliases: DNA helicase INO80 antibody, hINO80 antibody, homolog of yeast INO80 antibody, INO80 antibody, INO80 complex subunit A antibody, INO80 homolog antibody, INO80_HUMAN antibody, INO80A antibody, INOC1 antibody, KIAA1259 antibody, Putative DNA helicase INO80 complex homolog 1 antibody
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UniProt
- Q9ULG1
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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