CH25H 抗体 (AA 142-272)
Quick Overview for CH25H 抗体 (AA 142-272) (ABIN7147600)
抗原
See all CH25H 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 142-272
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Cholesterol 25-hydroxylase protein (142-272AA)
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亚型
- IgG
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anti-Cholesterol 25-Hydroxylase (CH25H) (AA 1-100) antibody
CH25H 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cholesterol 25-Hydroxylase (CH25H) (AA 206-272) antibodyCH25H 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cholesterol 25-Hydroxylase (CH25H) (AA 190-239) antibodyCH25H 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholesterol 25-Hydroxylase (CH25H) (AA 47-76) antibodyCH25H 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB55304 unconjugated
anti-Cholesterol 25-Hydroxylase (CH25H) (AA 142-247) antibodyCH25H 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G8 unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CH25H (Cholesterol 25-Hydroxylase (CH25H))
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别名
- CH25H
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背景
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Background: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes (PubMed:9852097). Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
Aliases: CH25H antibody, Cholesterol 25-hydroxylase antibody, EC 1.14.99.38 antibody, Cholesterol 25-monooxygenase antibody, h25OH antibody
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UniProt
- O95992
抗原
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