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HUS1 抗体 (AA 2-280) (HRP)

This HRP-conjugated 兔 多克隆 anti-HUS1 antibody specifically detects HUS1 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7147544
发货至: 中国
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Quick Overview for HUS1 抗体 (AA 2-280) (HRP) (ABIN7147544)

抗原

See all HUS1 抗体
HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

适用

  • 43
  • 21
  • 8

宿主

  • 54
  • 4

克隆类型

  • 56
  • 2
多克隆

标记

  • 28
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This HUS1 antibody is conjugated to HRP

应用范围

  • 30
  • 23
  • 13
  • 13
  • 10
  • 10
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
ELISA
  • 抗原表位

    • 15
    • 8
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-280

    原理

    HUS1 Antibody, HRP conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Checkpoint protein HUS1 protein (2-280AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

    别名

    HUS1

    背景

    Background: Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3\'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase.

    Aliases: Checkpoint protein HUS1 antibody, hHUS1 antibody, HUS1 (S. pombe) checkpoint homolog antibody, Hus1 antibody, HUS1 checkpoint homolog (S. pombe) antibody, HUS1 Checkpoint Protein antibody, HUS1 protein antibody, HUS1+ - like protein antibody, HUS1_HUMAN antibody, Hydroxyurea-sensitive 1, S. pombe, homolog of antibody

    UniProt

    O60921
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