HUS1 抗体 (AA 2-280) (Biotin)
Quick Overview for HUS1 抗体 (AA 2-280) (Biotin) (ABIN7147542)
抗原
See all HUS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-280
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Checkpoint protein HUS1 protein (2-280AA)
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亚型
- IgG
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anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) antibody
HUS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (Center) antibodyHUS1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) antibodyHUS1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) antibodyHUS1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 2-280) antibodyHUS1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) antibodyHUS1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) antibodyHUS1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) antibodyHUS1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) antibodyHUS1 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 2B12 unconjugated
anti-HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) antibodyHUS1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
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别名
- HUS1
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背景
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Background: Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3\'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase.
Aliases: Checkpoint protein HUS1 antibody, hHUS1 antibody, HUS1 (S. pombe) checkpoint homolog antibody, Hus1 antibody, HUS1 checkpoint homolog (S. pombe) antibody, HUS1 Checkpoint Protein antibody, HUS1 protein antibody, HUS1+ - like protein antibody, HUS1_HUMAN antibody, Hydroxyurea-sensitive 1, S. pombe, homolog of antibody
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UniProt
- O60921
抗原
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