MCAM 抗体 (AA 50-646)
Quick Overview for MCAM 抗体 (AA 50-646) (ABIN7147325)
抗原
See all MCAM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-646
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交叉反应
- 人
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纯化方法
- Protein G purified
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免疫原
- Recombinant Human Cell surface glycoprotein MUC18 protein (50-646AA)
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亚型
- IgG2a
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应用备注
- Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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别名
- CD146
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背景
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Background: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Aliases: Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146), MCAM, MUC18
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UniProt
- P43121
抗原
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