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MCAM 抗体 (AA 50-646)

This anti-MCAM antibody is a 小鼠 单克隆 antibody detecting MCAM in FACS, WB, IF 和 ELISA. Suitable for 人.
产品编号 ABIN7147325
发货至: 中国

Quick Overview for MCAM 抗体 (AA 50-646) (ABIN7147325)

抗原

See all MCAM 抗体
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

适用

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宿主

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小鼠

克隆类型

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  • 99
单克隆

标记

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This MCAM antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), ELISA

克隆位点

4D10C7
  • 抗原表位

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    AA 50-646

    交叉反应

    纯化方法

    Protein G purified

    免疫原

    Recombinant Human Cell surface glycoprotein MUC18 protein (50-646AA)

    亚型

    IgG2a
  • 应用备注

    Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    别名

    CD146

    背景

    Background: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

    Aliases: Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146), MCAM, MUC18

    UniProt

    P43121
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