RAD1 抗体 (AA 1-282)
Quick Overview for RAD1 抗体 (AA 1-282) (ABIN7147263)
抗原
See all RAD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-282
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Cell cycle checkpoint protein RAD1 protein (1-282AA)
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亚型
- IgG
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anti-Cell Cycle Checkpoint Protein RAD1 (RAD1) (AA 1-90) antibody
RAD1 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Cell Cycle Checkpoint Protein RAD1 (RAD1) antibodyRAD1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Cycle Checkpoint Protein RAD1 (RAD1) (AA 1-282) antibodyRAD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cell Cycle Checkpoint Protein RAD1 (RAD1) (Internal Region) antibodyRAD1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Cycle Checkpoint Protein RAD1 (RAD1) (AA 179-228) antibodyRAD1 适用: 人, Cow, 犬, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Cycle Checkpoint Protein RAD1 (RAD1) (Middle Region) antibodyRAD1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))
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别名
- RAD1
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背景
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Background: Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3\\\'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. Isoform 1 possesses 3\\\'->5\\\' double stranded DNA exonuclease activity.
Aliases: Cell cycle checkpoint protein Hrad1 antibody, Cell cycle checkpoint protein Rad 1 A / B antibody, Cell cycle checkpoint protein RAD1 antibody, Checkpoint control protein HRAD1 antibody, Checkpoint control protein RAD1 antibody, DNA repair exonuclease antibody, DNA repair exonuclease rad1 antibody, DNA repair exonuclease rad1 homolog antibody, DNA repair exonuclease REC1 antibody, DNA repair protein RAD1 antibody, EC 3.1.11.2 antibody, Exonuclease homolog RAD1 antibody, GTP-binding protein RAD antibody, hRAD 1 antibody, hRAD1 antibody, MGC77779 antibody, RAD 1 antibody, RAD antibody, RAD1 antibody, RAD1 homolog (S. pombe) antibody, RAD1 homolog antibody, Rad1 like DNA damage checkpoint antibody, Rad1 like DNA damage checkpoint protein antibody, RAD1, S. pombe, homolog of antibody, Rad1-like DNA damage checkpoint protein antibody, RAD1_HUMAN antibody, Ras associated with diabetes antibody, REC 1 antibody, REC1 antibody, RRAD antibody
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UniProt
- O60671
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途径
- M Phase
抗原
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