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RAD9A 抗体 (AA 267-341) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-RAD9A antibody specifically detects RAD9A in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7147256
发货至: 中国
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Quick Overview for RAD9A 抗体 (AA 267-341) (Biotin) (ABIN7147256)

抗原

See all RAD9A 抗体
RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

适用

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宿主

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克隆类型

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多克隆

标记

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This RAD9A antibody is conjugated to Biotin

应用范围

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ELISA
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    AA 267-341

    原理

    RAD9A Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Cell cycle checkpoint control protein RAD9A protein (267-341AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

    别名

    RAD9A

    背景

    Background: Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3\'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3\'->5\' double stranded DNA exonuclease activity. Its phosphorylation by PRKCD may be required for the formation of the 9-1-1 complex.

    Aliases: Cell cycle checkpoint control protein antibody, Cell cycle checkpoint control protein RAD9A antibody, DNA repair exonuclease rad9 homolog A antibody, hRAD 9 antibody, hRAD9 antibody, Rad 9 antibody, RAD 9A antibody, RAD9 (S pombe) homolog antibody, RAD9 homolog A antibody, RAD9 homolog antibody, Rad9a antibody, RAD9A_HUMAN antibody

    UniProt

    Q99638

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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