CD276 抗体 (AA 29-200)
Quick Overview for CD276 抗体 (AA 29-200) (ABIN7147148)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-200
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human CD276 antigen protein (29-200AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CD276
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别名
- CD276
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背景
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Background: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Aliases: 4Ig B7 H3 antibody, 4Ig-B7-H3 antibody, AU016588 antibody, B7 H3 antibody, B7 homolog 3 antibody, B7-H3 antibody, B7H3 antibody, B7RP-2 antibody, CD_antigen=CD276 antibody, CD276 antibody, CD276 antigen antibody, CD276 Molecule antibody, CD276_HUMAN antibody, Costimulatory molecule antibody, Flags: Precursor antibody, PSEC0249 antibody, UNQ309/PRO352 antibody
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UniProt
- Q5ZPR3
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途径
- Cancer Immune Checkpoints
抗原
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