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CD166 抗体 (AA 28-516)

This anti-CD166 antibody is a 兔 多克隆 antibody detecting CD166 in IHC, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7147124
发货至: 中国

Quick Overview for CD166 抗体 (AA 28-516) (ABIN7147124)

抗原

See all CD166 (ALCAM) 抗体
CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

适用

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宿主

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克隆类型

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多克隆

标记

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This CD166 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 28-516

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human CD166 antigen protein (28-516AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

    别名

    ALCAM

    背景

    Background: Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts (PubMed:7760007, PubMed:15496415, PubMed:15048703, PubMed:16352806, PubMed:23169771, PubMed:24945728). Promotes T-cell activation and proliferation via its interactions with CD6 (PubMed:15048703, PubMed:16352806, PubMed:24945728). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (PubMed:15294938, PubMed:16352806). Mediates homotypic interactions with cells that express ALCAM (PubMed:15496415, PubMed:16352806). Required for normal hematopoietic stem cell engraftment in the bone marrow (PubMed:24740813). Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction (PubMed:23169771). Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions (PubMed:15496415, PubMed:23169771). Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis, required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension, axon growth and axon guidance, axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).

    Aliases: Activated leukocyte cell adhesion molecule antibody, ALCAM antibody, ALCAM protein antibody, CD 166 antibody, CD166 antibody, CD166 antigen antibody, CD166_HUMAN antibody, FLJ3851 antibody, FLJ38514 antibody, MEMD antibody, MGC71733 antibody

    UniProt

    Q13740
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