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CTNNA1 抗体 (AA 1-288)

This 兔 多克隆 anti-CTNNA1 antibody specifically detects CTNNA1 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7146972
发货至: 中国
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Quick Overview for CTNNA1 抗体 (AA 1-288) (ABIN7146972)

抗原

See all CTNNA1 抗体
CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

适用

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宿主

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克隆类型

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多克隆

标记

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This CTNNA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 1-288

    原理

    CTNNA1 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Catenin alpha-1 protein (1-288AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

    别名

    CTNNA1

    背景

    Background: Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

    Aliases: Alpha E-catenin antibody, Cadherin associated protein 102 kDa antibody, Cadherin associated protein antibody, Cadherin-associated protein antibody, CAP 102 antibody, CAP102 antibody, Catenin (cadherin associated protein) alpha 1 102 kDa antibody, Catenin (cadherin associated protein), alpha 1, 102 kDa antibody, Catenin alpha 1 antibody, Catenin alpha-1 antibody, CTNA1_HUMAN antibody, CTNNA 1 antibody, Ctnna1 antibody, FLJ36832 antibody, FLJ52416 antibody, MDPT2 antibody, NY REN 13 antigen antibody, OTTHUMP00000224141 antibody, OTTHUMP00000224147 antibody, Renal carcinoma antigen NY REN 13 antibody, Renal carcinoma antigen NY-REN-13 antibody

    UniProt

    P35221

    途径

    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location
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