MAP4K4 抗体 (pSer801)
Quick Overview for MAP4K4 抗体 (pSer801) (ABIN710381)
抗原
See all MAP4K4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - pSer801
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交叉反应
 - 人, 大鼠
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预测反应
 - Mouse,Dog,Horse,Chicken,Rabbit
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic phosphopeptide derived from human MAP4K4 around the phosphorylation site of Ser801
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亚型
 - IgG
 
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应用备注
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                        WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
 - 12 months
 
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- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
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别名
 - MAP4K4
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背景
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Synonyms: MAP4K4phospho S801, Hepatocyte progenitor kinase like/germinal center kinase like kinase, HGK, HPK/GCK like kinase, HPK/GCK like kinase HGK, KIAA0687, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, MEKKK4, Mitogen activated protein kinase kinase kinase kinase 4, Nck interacting kinase, NIK.
Background: MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport.
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基因ID
 - 338376
 
抗原
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