BRAP 抗体 (AA 13-124) (HRP)
Quick Overview for BRAP 抗体 (AA 13-124) (HRP) (ABIN7145761)
抗原
See all BRAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 13-124
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human BRCA1-associated protein (13-124AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BRAP (BRCA1 Associated Protein (BRAP))
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别名
- BRAP
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背景
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Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Aliases: BRAP antibody, RNF52BRCA1-associated protein antibody, EC 2.3.2.27 antibody, BRAP2 antibody, Impedes mitogenic signal propagation antibody, IMP antibody, RING finger protein 52 antibody, RING-type E3 ubiquitin transferase BRAP2 antibody, Renal carcinoma antigen NY-REN-63 antibody
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UniProt
- Q7Z569
抗原
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