MAP4K4 抗体 (pSer629) (Biotin)
Quick Overview for MAP4K4 抗体 (pSer629) (Biotin) (ABIN710353)
抗原
See all MAP4K4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer629
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预测反应
- Human,Mouse,Rat,Dog,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human MAP4K4 around the phosphorylation site of Ser629
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亚型
- IgG
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
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别名
- MAP4K4
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背景
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Synonyms: MAP4K4phospho S629, Hepatocyte progenitor kinase like/germinal center kinase like kinase, HGK, HPK/GCK like kinase, HPK/GCK like kinase HGK, KIAA0687, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, MEKKK4, Mitogen activated protein kinase kinase kinase kinase 4, Nck interacting kinase, NIK.
Background: MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport.
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基因ID
- 9448
抗原
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