Klotho beta 抗体 (AA 1-130)
Quick Overview for Klotho beta 抗体 (AA 1-130) (ABIN7145515)
抗原
See all Klotho beta (KLB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-130
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Beta-klotho protein (1-130AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Klotho beta (KLB)
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别名
- KLB
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背景
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Background: Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).
Aliases: Beta-klotho antibody, BetaKlotho antibody, BKL antibody, KLB antibody, KLOTB_HUMAN antibody, Klotho beta like protein antibody, Klotho beta-like protein antibody
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UniProt
- Q86Z14
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
抗原
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