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Klotho beta 抗体 (Middle Region)

KLB 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN635626
发货至: 中国
  • 抗原 See all Klotho beta (KLB) 抗体
    Klotho beta (KLB)
    抗原表位
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 17
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 23
    • 1
    克隆类型
    • 23
    • 1
    多克隆
    标记
    • 14
    • 7
    • 2
    • 1
    This Klotho beta antibody is un-conjugated
    应用范围
    • 19
    • 13
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Klotho Beta antibody was raised against the middle region of KLB
    纯化方法
    Affinity purified
    免疫原
    Klotho Beta antibody was raised using the middle region of KLB corresponding to a region with amino acids DAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGFSLKESTPDVQG
    Top Product
    Discover our top product KLB Primary Antibody
  • 应用备注
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    Klotho Beta Blocking Peptide, catalog no. 33R-1868, is also available for use as a blocking control in assays to test for specificity of this Klotho Beta antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KLB antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    Klotho beta (KLB)
    别名
    Klotho beta (KLB 产品)
    别名
    KLB antibody, BKL antibody, AV071179 antibody, betaKlotho antibody, Klb-ps1 antibody, RGD1308227 antibody, klotho beta antibody, KLB antibody, Klb antibody
    背景
    KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.
    分子量
    120 kDa (MW of target protein)
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
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