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BNIP3 抗体 (AA 1-164)

The 兔 多克隆 anti-BNIP3 antibody is suitable to detect BNIP3 in samples from 人. It has been validated for IHC, ELISA 和 IF.
产品编号 ABIN7145331
发货至: 中国
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Quick Overview for BNIP3 抗体 (AA 1-164) (ABIN7145331)

抗原

See all BNIP3 抗体
BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

适用

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宿主

  • 95
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克隆类型

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多克隆

标记

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This BNIP3 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 1-164

    原理

    BNIP3 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein (1-164AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

    别名

    BNIP3

    背景

    Background: Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.

    Aliases: BCL2 Adenovirus E1B 19 kDa Interacting Protein 3 antibody, BCL2/adenovirus E1B 19 kDa protein interacting protein 3 antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody, BNIP 3 antibody, BNIP3 antibody, BNIP3_HUMAN antibody, NIP 3 antibody, NIP3 antibody

    UniProt

    Q12983

    途径

    Autophagy, Brown Fat Cell Differentiation
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