BNIP3 抗体 (AA 1-164)
Quick Overview for BNIP3 抗体 (AA 1-164) (ABIN7145331)
抗原
See all BNIP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-164
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein (1-164AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
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别名
- BNIP3
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背景
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Background: Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.
Aliases: BCL2 Adenovirus E1B 19 kDa Interacting Protein 3 antibody, BCL2/adenovirus E1B 19 kDa protein interacting protein 3 antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody, BNIP 3 antibody, BNIP3 antibody, BNIP3_HUMAN antibody, NIP 3 antibody, NIP3 antibody
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UniProt
- Q12983
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途径
- Autophagy, Brown Fat Cell Differentiation
抗原
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