BBS2 抗体 (AA 1-96)
Quick Overview for BBS2 抗体 (AA 1-96) (ABIN7145239)
抗原
See all BBS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-96
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交叉反应
- 人, 小鼠
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Bardet-Biedl syndrome 2 protein (1-96AA)
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亚型
- IgG
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anti-Bardet-Biedl Syndrome 2 (BBS2) (C-Term) antibody
BBS2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) antibodyBBS2 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (AA 1-721) antibodyBBS2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (AA 151-200) antibodyBBS2 适用: 人, 犬, Cow, 马, 兔, 斑马鱼, 豚鼠, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (AA 315-364) antibodyBBS2 适用: 人, 小鼠, 犬, Cow, 马, 兔, 斑马鱼, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 2 (BBS2) (N-Term) antibodyBBS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BBS2 (Bardet-Biedl Syndrome 2 (BBS2))
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别名
- BBS2
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背景
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Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
Aliases: BBS2Bardet-Biedl syndrome 2 protein antibody
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UniProt
- Q9BXC9
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途径
- Hedgehog Signaling
抗原
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