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BBS1 抗体 (AA 217-417) (HRP)

BBS1 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7145234
发货至: 中国
  • 抗原 See all BBS1 抗体
    BBS1 (Bardet-Biedl Syndrome 1 (BBS1))
    抗原表位
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 217-417
    适用
    • 21
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 19
    • 1
    • 1
    克隆类型
    • 21
    多克隆
    标记
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BBS1 antibody is conjugated to HRP
    应用范围
    • 11
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Bardet-Biedl syndrome 1 protein (217-417AA)
    亚型
    IgG
    Top Product
    Discover our top product BBS1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    BBS1 (Bardet-Biedl Syndrome 1 (BBS1))
    别名
    BBS1 (BBS1 产品)
    别名
    im:7144669 antibody, bbs2l2 antibody, BBS1 antibody, DKFZp468B1612 antibody, BBS2L2 antibody, AI451249 antibody, D19Ertd609e antibody, Bardet-Biedl syndrome 1 antibody, bardet-biedl syndrome 1 antibody, Bardet-Biedl syndrome 1 (human) antibody, BBS1 antibody, bbs1 antibody, Bbs1 antibody
    背景

    Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.

    Aliases: AI451249 antibody, Bardet-Biedl syndrome 1 antibody, Bardet-Biedl syndrome 1 homolog antibody, Bardet-Biedl syndrome 1 protein antibody, BBS1 antibody, BBS1_HUMAN antibody, BBS2-like protein 2 antibody, BBS2L2 antibody, D19Ertd609e antibody

    UniProt
    Q8NFJ9
    途径
    Hedgehog Signaling
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