ARID1A 抗体 (AA 655-816)
Quick Overview for ARID1A 抗体 (AA 655-816) (ABIN7144775)
抗原
See all ARID1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 655-816
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human AT-rich interactive domain-containing protein 1A protein (655-816AA)
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亚型
- IgG
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anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) antibody
ARID1A 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (AA 1930-1964) antibodyARID1A 适用: 人 WB 宿主: 兔 Polyclonal RB53541 unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (AA 1717-1750) antibodyARID1A 适用: 人 WB 宿主: 兔 Polyclonal RB53540 unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (Internal Region) antibodyARID1A 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
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别名
- ARID1A
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背景
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Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Aliases: actin-dependent regulator of chromatin subfamily F member 1 antibody, ARI1A_HUMAN antibody, ARID domain containing protein 1A antibody, ARID domain-containing protein 1A antibody, ARID1A antibody, AT rich interactive domain 1A (SWI like) antibody, AT rich interactive domain 1A antibody, AT rich interactive domain containing protein 1A antibody, AT-rich interactive domain-containing protein 1A antibody, B120 antibody, BAF250 antibody, BAF250A antibody, BM029 antibody, brain protein 120 antibody, BRG1 associated factor 250 antibody, BRG1 associated factor 250a antibody, BRG1-associated factor 250 antibody, BRG1-associated factor 250a antibody, C1ORF4 antibody, chromatin remodeling factor p250 antibody, chromosome 1 open reading frame 4 antibody, ELD antibody, hELD antibody, hOSA1 antibody, matrix-associated antibody, MRD14 antibody, Osa homolog 1 antibody, OSA1 antibody, OSA1 nuclear protein antibody, P270 antibody, SMARCF1 antibody, SWI like protein antibody, SWI SNF complex protein p270 antibody, SWI-like protein antibody, SWI/SNF complex protein p270 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1 antibody, SWI/SNF-related antibody
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UniProt
- O14497
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
抗原
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