Aryl Hydrocarbon Receptor 抗体 (AA 126-353)
Quick Overview for Aryl Hydrocarbon Receptor 抗体 (AA 126-353) (ABIN7144657)
抗原
See all Aryl Hydrocarbon Receptor (AHR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 126-353
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Aryl hydrocarbon receptor protein (126-353AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Aryl Hydrocarbon Receptor (AHR)
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别名
- AHR
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背景
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Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Aliases: Ah receptor antibody, AhR antibody, AHR_HUMAN antibody, Aromatic hydrocarbon receptor antibody, Aryl hydrocarbon receptor antibody, Aryl hydrocarbon receptor precursor antibody, bHLHe76 antibody, Class E basic helix loop helix protein 76 antibody, Class E basic helix-loop-helix protein 76 antibody, HGNC:348 antibody
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UniProt
- P35869
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途径
- Regulation of Cell Size
抗原
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