Ensa 抗体 (AA 1-121)
Quick Overview for Ensa 抗体 (AA 1-121) (ABIN7143861)
抗原
See all Ensa (ENSA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-121
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Alpha-endosulfine protein (1-121AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Ensa (ENSA) (Endosulfine alpha (ENSA))
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别名
- ENSA
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背景
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Background: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase.Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.
Aliases: ENSAAlpha-endosulfine antibody, ARPP-19e antibody
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UniProt
- O43768
抗原
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