AKR1C4 抗体 (AA 1-323)
Quick Overview for AKR1C4 抗体 (AA 1-323) (ABIN7143695)
抗原
See all AKR1C4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-323
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Aldo-keto reductase family 1 member C4 protein (1-323AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
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别名
- AKR1C4
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背景
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Background: Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Aliases: 3 alpha HSD1 antibody, 3-alpha-HSD1 antibody, 3-alpha-hydroxysteroid dehydrogenase type I antibody, AK1C4_HUMAN antibody, AKR1C4 antibody, Aldo keto reductase family 1 member C4 antibody, Aldo-keto reductase family 1 member C4 antibody, CDR antibody, Chlordecone reductase antibody, DD-4 antibody, DD4 antibody, Dihydrodiol dehydrogenase 4 antibody, HAKRA antibody, HSD3a antibody
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UniProt
- P17516
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途径
- Steroid Hormone Biosynthesis
抗原
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