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ARF1 抗体 (AA 2-181) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-ARF1 antibody specifically detects ARF1 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7143443
发货至: 中国
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Quick Overview for ARF1 抗体 (AA 2-181) (Biotin) (ABIN7143443)

抗原

See all ARF1 抗体
ARF1 (ADP-Ribosylation Factor 1 (ARF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ARF1 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

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    AA 2-181

    原理

    ARF1 Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human ADP-ribosylation factor 1 protein (2-181AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ARF1 (ADP-Ribosylation Factor 1 (ARF1))

    别名

    ARF1

    背景

    Background: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity, the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).

    Aliases: ADP Ribosylation Factor 1 antibody, ADP-ribosylation factor 1 antibody, ARF 1 antibody, ARF1 antibody, ARF1_HUMAN antibody

    UniProt

    P84077

    途径

    Transition Metal Ion Homeostasis, Inositol Metabolic Process
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