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Serotonin Receptor 2B 抗体 (AA 382-481)

This anti-Serotonin Receptor 2B antibody is a 兔 多克隆 antibody detecting Serotonin Receptor 2B in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7142626
发货至: 中国

Quick Overview for Serotonin Receptor 2B 抗体 (AA 382-481) (ABIN7142626)

抗原

See all Serotonin Receptor 2B (HTR2B) 抗体
Serotonin Receptor 2B (HTR2B)

适用

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宿主

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克隆类型

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多克隆

标记

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This Serotonin Receptor 2B antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 382-481

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human 5-hydroxytryptamine receptor 2B protein (382-481AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Serotonin Receptor 2B (HTR2B)

    别名

    HTR2B

    背景

    Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity. May play a role in the perception of pain. Plays a role in the regulation of behavior, including impulsive behavior. Required for normal proliferation of embryonic cardiac myocytes and normal heart development. Protects cardiomyocytes against apoptosis. Plays a role in the adaptation of pulmonary arteries to chronic hypoxia. Plays a role in vasoconstriction. Required for normal osteoblast function and proliferation, and for maintaining normal bone density. Required for normal proliferation of the interstitial cells of Cajal in the intestine.

    Aliases: 5 HT 2B antibody, 5 HT 2B receptor antibody, 5 HT(2B) antibody, 5 HT2B antibody, 5 hydroxytryptamine (serotonin) receptor 2B antibody, 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled antibody, 5 hydroxytryptamine 2B receptor antibody, 5 hydroxytryptamine receptor 2B antibody, 5-HT-2B antibody, 5-HT2B antibody, 5-hydroxytryptamine receptor 2B antibody, 5HT(2B) antibody, 5HT2B Receptor antibody, 5HT2B_HUMAN antibody, 5HT2F antibody, Htr 2b antibody, Htr2b antibody, NP75 protein antibody, SEROTONIN 5HT2B RECEPTOR antibody, Serotonin receptor 2B antibody, Stomach fundus serotonin receptor antibody

    UniProt

    P41595

    途径

    JAK/STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
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