HTR2A 抗体 (AA 385-471) (Biotin)
Quick Overview for HTR2A 抗体 (AA 385-471) (Biotin) (ABIN7142623)
抗原
See all HTR2A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 385-471
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human 5-hydroxytryptamine receptor 2A protein (385-471AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
-
别名
- HTR2A
-
背景
-
Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca2+ ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.
Aliases: 5 HT 2 antibody, 5 HT 2A antibody, 5 HT2 receptor antibody, 5 HT2A antibody, 5 hydroxytryptamine receptor 2A antibody, 5-HT-2 antibody, 5-HT-2A antibody, 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled antibody, 5-hydroxytryptamine 2A receptor antibody, 5-hydroxytryptamine receptor 2A antibody, 5HT2A_HUMAN antibody, HTR 2 antibody, HTR 2A antibody, HTR2 antibody, HTR2, formerly antibody, HTR2A antibody, serotonin 5-HT-2 receptor, formerly antibody, serotonin 5-HT-2A receptor antibody, Serotonin receptor 2A antibody
-
UniProt
- P28223
-
途径
- JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
-