RNASEL 抗体 (AA 330-741) (FITC)
Quick Overview for RNASEL 抗体 (AA 330-741) (FITC) (ABIN7142132)
抗原
See all RNASEL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 330-741
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human 2-5A-dependent ribonuclease protein (330-741AA)
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亚型
- IgG
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anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) (AA 472-741) antibody
RNASEL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) antibodyRNASEL 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) (AA 358-583) antibodyRNASEL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) (AA 330-741) antibodyRNASEL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) (AA 619-728) antibodyRNASEL 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) (AA 619-728) antibodyRNASEL 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3B4 unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) (AA 140-167), (N-Term) antibodyRNASEL 适用: 小鼠 WB 宿主: 兔 Polyclonal RB37131 unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) antibodyRNASEL 适用: 人, 猴 WB, ELISA 宿主: 小鼠 Monoclonal (2E9) unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))
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别名
- RNASEL
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背景
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Background: Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes. RNASEL mediated apoptosis is the result of a JNK-dependent stress-response pathway leading to cytochrome c release from mitochondria and caspase-dependent apoptosis. Therefore, activation of RNASEL could lead to elimination of virus infected cells under some circumstances. Might play a central role in the regulation of mRNA turnover.
Aliases: 2 5A dependent ribonuclease antibody, 2 5A dependent RNase antibody, 2' 5' oligoisoadenylate synthetase dependent antibody, 2-5A-dependent ribonuclease antibody, 2-5A-dependent RNase antibody, DKFZp781D08126 antibody, Interferon induced 2 5A dependent RNase antibody, MGC104972 antibody, MGC133329 antibody, PRCA 1 antibody, PRCA1 antibody, Ribonuclease 4 antibody, Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) antibody, Ribonuclease L antibody, Ribonuclease4 antibody, RibonucleaseL antibody, RN5A_HUMAN antibody, RNase L antibody, Rnasel antibody, RNS 4 antibody, RNS4 antibody
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UniProt
- Q05823
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途径
- Hepatitis C
抗原
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