CRP 抗体 (AA 1-210) (Biotin)
Quick Overview for CRP 抗体 (AA 1-210) (Biotin) (ABIN7141407)
抗原
See all CRP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-210
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交叉反应
- E. coli
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Escherichia coli cAMP-activated global transcriptional regulator CRP protein (1-210AA)
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亚型
- IgG
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anti-C-Reactive Protein (CRP) (AA 17-224) antibody
CRP 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 20-222) antibodyCRP 适用: Pig WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 1-224) antibodyCRP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 14-224) antibodyCRP 适用: Cow WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) antibodyCRP 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1G1 unconjugated
anti-C-Reactive Protein (CRP) (AA 20-225) antibodyCRP 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (Internal Region) antibodyCRP 适用: 人, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 125-224) antibodyCRP 适用: 人, 小鼠, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) antibodyCRP 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 20-230) antibodyCRP 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CRP (C-Reactive Protein (CRP))
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别名
- crp
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背景
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Background: A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding (to consensus sequence 5\'-AAATGTGATCTAGATCACATTT-3\') to directly regulate the transcription of about 300 genes in about 200 operons and indirectly regulate the expression of about half the genome. There are 3 classes of CRP promoters, class I promoters have a single CRP-binding site upstream of the RNA polymerase (RNAP)-binding site, whereas in class II promoters the single CRP- and RNAP-binding site overlap, CRP making multiple contacts with RNAP. Class III promoters require multiple activator molecules, including at least one CRP dimer. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA (about 87 degrees), bringing upstream promoter elements into contact with RNAP. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP. High levels of active CRP are detrimental to growth.Plays a major role in carbon catabolite repression (CCR). CCR involves cAMP, adenylate cyclase (cyaA), CRP and the EIIA-Glc component of the PTS (crr). In the presence of glucose EIIA-Glc is dephosphorylated, and does not activate adenylate cyclase, leading to reduced cAMP and thus decreased CRP activity. Also plays a role in many other processes
Aliases: crp antibody, cap antibody, csm antibody, b3357 antibody, JW5702cAMP-activated global transcriptional regulator CRP antibody, Catabolite activator protein antibody, CAP antibody, Catabolite gene activator antibody, cAMP receptor protein antibody, CRP antibody, cAMP regulatory protein antibody
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UniProt
- P0ACJ8
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途径
- Carbohydrate Homeostasis
抗原
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