BRAP 抗体
Quick Overview for BRAP 抗体 (ABIN7140299)
抗原
See all BRAP 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Affinity purified
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免疫原
- Purified recombinant human BRAP protein fragments expressed in E.coli.
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亚型
- IgG1, IgG1 kappa
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应用备注
- Recommended dilution:WB:1:500-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified mouse monoclonal antibody in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BRAP (BRCA1 Associated Protein (BRAP))
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别名
- BRAP
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背景
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Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Aliases: 3010002G07Rik, BRAP2, BRCA1 associated protein, EC 6.3.2., Galectin 2 binding protein, IMP, Impedes mitogenic signal propagation, Renal carcinoma antigen NY REN 63, RING finger protein 52, RNF52, zgc:92894.
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UniProt
- Q7Z569
抗原
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