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BRAP 抗体

This anti-BRAP antibody is a 小鼠 单克隆 antibody detecting BRAP in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7140299
发货至: 中国

Quick Overview for BRAP 抗体 (ABIN7140299)

抗原

See all BRAP 抗体
BRAP (BRCA1 Associated Protein (BRAP))

适用

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宿主

  • 25
小鼠

克隆类型

  • 25
单克隆

标记

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This BRAP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 交叉反应

    纯化方法

    Affinity purified

    免疫原

    Purified recombinant human BRAP protein fragments expressed in E.coli.

    亚型

    IgG1, IgG1 kappa
  • 应用备注

    Recommended dilution:WB:1:500-1:5000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified mouse monoclonal antibody in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BRAP (BRCA1 Associated Protein (BRAP))

    别名

    BRAP

    背景

    Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

    Aliases: 3010002G07Rik, BRAP2, BRCA1 associated protein, EC 6.3.2., Galectin 2 binding protein, IMP, Impedes mitogenic signal propagation, Renal carcinoma antigen NY REN 63, RING finger protein 52, RNF52, zgc:92894.

    UniProt

    Q7Z569
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