RTN4RL2 抗体 (AA 355-372) (HRP)
Quick Overview for RTN4RL2 抗体 (AA 355-372) (HRP) (ABIN7140117)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 355-372
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Peptide sequence from Human Reticulon-4 receptor-like 2 protein (355-372AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))
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别名
- RTN4RL2
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背景
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Background: Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity). Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis, protection against apoptosis is probably mediated by MAG (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed: 22325200). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed: 22325200).
Aliases: RTN4RL2 antibody, NGRH1 antibody, NGRL3 antibody, Reticulon-4 receptor-like 2 antibody, Nogo receptor-like 3 antibody, Nogo-66 receptor homolog 1 antibody, Nogo-66 receptor-related protein 2 antibody, NgR2 antibody
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UniProt
- Q86UN3
抗原
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