OPRK1 抗体 (AA 31-50) (FITC)
Quick Overview for OPRK1 抗体 (AA 31-50) (FITC) (ABIN7139901)
抗原
See all OPRK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-50
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Peptide sequence from Human Kappa-type opioid receptor protein (31-50AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- OPRK1 (Opioid Receptor, kappa 1 (OPRK1))
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别名
- OPRK1
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背景
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Background: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
Aliases: K-OR-1 antibody, Kappa opioid receptor antibody, Kappa type opioid receptor antibody, Kappa-type opioid receptor antibody, KOR 1 antibody, KOR antibody, KOR-1 antibody, Opiate receptor kappa 1 antibody, Opiate receptor, kappa 1 antibody, Opioid receptor, kappa 1 antibody, OPRK 1 antibody, OPRK antibody, OPRK_HUMAN antibody, OPRK1 antibody, Oprk2 antibody, R21 antibody
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UniProt
- P41145
抗原
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