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Cadherin 5 抗体 (pTyr731)

The 兔 多克隆 anti-Cadherin 5 antibody (ABIN7139104) specifically detects Cadherin 5 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7139104
发货至: 中国
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Quick Overview for Cadherin 5 抗体 (pTyr731) (ABIN7139104)

抗原

See all Cadherin 5 (CDH5) 抗体
Cadherin 5 (CDH5)

适用

  • 96
  • 69
  • 44
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 94
  • 28
  • 7
  • 1

克隆类型

  • 81
  • 49
多克隆

标记

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  • 1
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This Cadherin 5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 16
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    • 6
    • 3
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    • 3
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    pTyr731

    原理

    Phospho-CDH5 (Tyr731) Antibody

    交叉反应

    小鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Tyrosine731 (H-I-Y(p)-G-Y) derived from Human VE-Cadherin.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Cadherin 5 (CDH5)

    别名

    CDH5

    背景

    Background:

    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen.

    Wessel F, et al. (2014) Nat Immunol 15, 223-30
    Sawada J, et al. (2012) Cancer Cell 22, 235-49
    Turowski P, et al. (2008) J Cell Sci 121, 29-37

    Aliases: 7B 4 antibody, 7B4 antibody, 7B4 antigen antibody, CADH5_HUMAN antibody, Cadherin 5 antibody, Cadherin 5 type 2 antibody, Cadherin 5, type 2 (vascular endothelium) antibody, Cadherin 5, type 2, VE cadherin (vascular epithelium) antibody, cadherin, vascular endothelial antibody, cadherin, vascular endothelial, 1 antibody, Cadherin-5 antibody, Cadherin5 antibody, CD 144 antibody, CD144 antibody, CD144 antigen antibody, CDH 5 antibody, CDH5 antibody, CDH5 protein antibody, Endothelial specific cadherin antibody, FLJ17376 antibody, OTTHUMP00000174777 antibody, Vascular endothelial cadherin antibody, Vascular epithelium cadherin antibody, VE Cad antibody, VE-cadherin antibody, VEC antibody

    UniProt

    P33151

    途径

    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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