Cadherin 5 抗体 (pTyr731)
Quick Overview for Cadherin 5 抗体 (pTyr731) (ABIN7139104)
抗原
See all Cadherin 5 (CDH5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr731
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交叉反应
- 人, 小鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of Tyrosine731 (H-I-Y(p)-G-Y) derived from Human VE-Cadherin.
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亚型
- IgG
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应用备注
- WB:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Cadherin 5 (CDH5)
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别名
- CDH5
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背景
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Background:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen.
Wessel F, et al. (2014) Nat Immunol 15, 223-30
Sawada J, et al. (2012) Cancer Cell 22, 235-49
Turowski P, et al. (2008) J Cell Sci 121, 29-37Aliases: 7B 4 antibody, 7B4 antibody, 7B4 antigen antibody, CADH5_HUMAN antibody, Cadherin 5 antibody, Cadherin 5 type 2 antibody, Cadherin 5, type 2 (vascular endothelium) antibody, Cadherin 5, type 2, VE cadherin (vascular epithelium) antibody, cadherin, vascular endothelial antibody, cadherin, vascular endothelial, 1 antibody, Cadherin-5 antibody, Cadherin5 antibody, CD 144 antibody, CD144 antibody, CD144 antigen antibody, CDH 5 antibody, CDH5 antibody, CDH5 protein antibody, Endothelial specific cadherin antibody, FLJ17376 antibody, OTTHUMP00000174777 antibody, Vascular endothelial cadherin antibody, Vascular epithelium cadherin antibody, VE Cad antibody, VE-cadherin antibody, VEC antibody
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UniProt
- P33151
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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