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KIT 抗体 (pTyr936)

The 兔 多克隆 anti-KIT antibody (ABIN7139089) specifically detects KIT in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7139089
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for KIT 抗体 (pTyr936) (ABIN7139089)

抗原

See all KIT 抗体
KIT (Mast/stem Cell Growth Factor Receptor (KIT))

适用

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克隆类型

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多克隆

标记

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This KIT antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    pTyr936

    原理

    Phospho-KIT (Tyr936) Antibody

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of tyrosine 936 (H-I-Y(p)-S-N) derived from Human c-Kit.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    KIT (Mast/stem Cell Growth Factor Receptor (KIT))

    别名

    KIT

    背景

    Background: This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)

    Martin, F.H. et al. (1990) Cell 63, 203-11.
    Blume-Jensen, P. et al. (2000) Nat Genet 24, 157-62.
    Gommerman, J.L. et al. (1997) J Biol Chem 272, 30519-25.
    Nocka, K. et al. (1990) EMBO J 9, 1805-13.

    Aliases: C Kit antibody, c-Kit antibody, c-Kit Ligand antibody, CD117 antibody, Kit antibody, Kit Ligand antibody, KIT oncogene antibody, KIT proto oncogene receptor tyrosine kinase antibody, KIT_HUMAN antibody, Mast cell growth factor receptor antibody, Mast/stem cell growth factor receptor Kit antibody, MGF antibody, p145 c-kit antibody, PBT antibody, Piebald trait protein antibody, Proto oncogene c Kit antibody, Proto oncogene tyrosine protein kinase Kit antibody, Proto-oncogene c-Kit antibody, SCF Receptor antibody, SCFR antibody, soluble KIT variant 1 antibody, Steel Factor Receptor antibody, Stem cell factor receptor antibody, tyrosine protein kinase Kit antibody, Tyrosine-protein kinase Kit antibody, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein antibody, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody

    UniProt

    P10721

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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